Does acupuncture improve IVF success rates?

Reviewed by

Dr. Susan G. Schiff, A.P., DOM

Last reviewed:

The evidence is mixed, and any practice that tells you otherwise is selling. A 2002 German trial of 160 women reported a clinical pregnancy rate of 42.5 percent with acupuncture before and after embryo transfer against 26.3 percent without it. The largest trial since, 848 women in Australia published in JAMA in 2018, found no difference in live births between real acupuncture and sham acupuncture at transfer. What is consistent is lower anxiety in the acupuncture groups, and IVF is a process in which that matters.

Why do the studies disagree?

Three reasons. First, the early trials compared acupuncture with no treatment, while later trials compared it with sham acupuncture, needling at non-points or with non-penetrating needles. Sham acupuncture is not inert: it still touches the skin, still involves rest and attention, and in trial after trial it produces some of the same physiological response. When both arms improve, the difference between them shrinks.

Second, clinic baseline rates rose. The 2002 trial's control rate of 26 percent is well below what many clinics achieve today, which leaves less room for an add-on to show an effect. Third, the protocols differ: a single session on transfer day, which is what most trials tested, is not the same intervention as a three-month course before stimulation, which is what the practice offers and which has been studied far less.

What could plausibly help, mechanically?

Two measured effects are relevant to IVF. Acupuncture at lower-abdominal and sacral points has been shown on Doppler ultrasound to reduce uterine artery resistance, which means better blood flow to the endometrium in the weeks the lining is being built. And acupuncture lowers cortisol and anxiety scores, which matters because the hypothalamic-pituitary-ovarian axis is sensitive to stress signaling. Neither effect guarantees an embryo implants; both are reasonable things to want during a cycle.

So is it worth doing?

For most patients the decision rests on three things: whether they want support for the anxiety of the cycle, whether they have cycle-regulation or lining concerns their physician has flagged, and whether the cost and time fit. Acupuncture does not interfere with stimulation medications or transfer, and reproductive endocrinologists in South Florida routinely work alongside acupuncturists. What it should never do is delay or replace the IVF plan itself.

Common questions

What does the 42.5 percent versus 26.3 percent figure mean?

It is the clinical pregnancy rate from the 2002 Paulus trial: 34 of 80 women who had acupuncture before and after transfer became pregnant, against 21 of 80 who did not. It is a real result from a small trial with no sham control, and later, larger trials did not reproduce it. Quote it as history, not as a promise.

Does acupuncture help with the side effects of stimulation drugs?

Many patients report less bloating, better sleep, and steadier mood during stimulation, and the anxiety reduction is the best-documented benefit in the trials. These are supportive effects; report any severe bloating or pain to your IVF clinic, since ovarian hyperstimulation needs medical care.

Will my IVF clinic object?

Most do not. Tell your clinic you are having acupuncture and share any herbal formula with them; the practice adjusts or pauses herbs during stimulation when a physician prefers it.

General information, not medical advice. Acupuncture and Chinese herbal medicine support, and do not replace, care from your physician. Whether treatment fits your situation is decided at a first visit.